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. Author manuscript; available in PMC: 2020 Mar 3.
Published in final edited form as: Chem Res Toxicol. 2019 Sep 11;32(10):1997–2005. doi: 10.1021/acs.chemrestox.9b00149

Figure 3.

Figure 3.

APZ and AY9944 potentiate O3-induced IL-6 and IL-8 expression 16HBE cells grown at ALI treated in the basolateral compartment with lfiM APZ or AY9944 for 3 days prior to 0.4 03 exposure yielded enhanced expression of (A) IL-6 and (C) IL-8 for APZ and (B) IL-6 (D) IL-8 for AY9944 with significant increases in both markers compared to the DMSO control. n = 3–5. Data are presented as mean ± SEM. Statistical analysis was performed using a two-way ANOVA and Fishers LSD post hoc test. *p < 0.05, **p <0.01.