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. 2020 Mar 3;15(3):e0229994. doi: 10.1371/journal.pone.0229994

Table 3. Factors associated with SVR12.

SVR12 (n = 108) Non-SVR12 (n = 2) p-value
Age (yrs) 65.7±10.4 61.2±7.4 0.509
Male gender, n (%) 62 (57) 1 (50) 1.000
Prior IFN, n (%) 62 (57) 2 (100) 0.509
Cirrhosis, n (%) 73 (68) 2 (100) 1.000
HCC, n (%) 11 (10) 0 (0) 1.000
AST (U/L) 87±52 55±4 0.381
ALT (U/L) 85±82 37±7 0.416
Platelet (103/μL) 133±49 151±27 0.353
FIB-4 4.8±3.2 3.3±1.4 0.502
Genotype 1a/1b 4/104 0/2 1.000
Log HCV RNA (IU/mL) 5.9±0.9 6.8±0.0 0.057
Log HCV Ag (fmol/L) 3.4±0.8 4.4±0.5 0.056

Abbreviation: SVR12, sustained virological response12 weeks off therapy; IFN, interferon; HCC, hepatocellular carcinoma; AST, aspartate aminotransferase; ALT, alanine aminotransferase; FIB-4, fibrosis index based on 4 factors; HCV, hepatitis C virus