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Individual fractional DNL in traditional ultracentrifugation versus immunoaffinity fractions. Fractional DNL measured in 4 healthy adults (subjects 5–8) over 5 h of stable-isotope tracer study. Mean DNL AUC × 5 h (study time 3–8 h) ± standard error of the mean, n = 4: TRL, 46.9 ± 8.5; CMIA, 19.3 ± 8; CMU, 40.8 ± 8.2; CMU+IA 14.6 ± 4.1. DNL AUC P-value, n = 4: CMU versus CMIA, P = 0.0621; CMU versus CMU+IA, P = 0.0153; CMIA versus CMU+IA, P = 0.4511.
