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CORM-3 ameliorates impairments in locomotor and exploratory activities after HSR. (A) Distance, (B) speed, (C) rearing, (D) time in corner and (E) grooming of each group on day 7 after HSR. Data are presented as the mean ± SD (n=12 per group). *P<0.05 vs. Sham; #P<0.05 vs. HSR vehicle and HSR iCORM-3. CORM, carbon monoxide-releasing molecule; HSR, hemorrhage shock and resuscitation; iCORM-3, inactive CORM-3.
