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. 2020 Feb 7;45(4):1176–1186. doi: 10.3892/ijmm.2020.4493

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Copyright: © Fu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Time course of in vivo localized ¹H MR spectra in the hippocampus induced by the indicated stimuli. (A) Representative ¹H MR spectra of the hippocampus in the coronal view at 3, 6, 12 and 24 h after HSR treatment. (B-D) The time course of NAA/Cr, mI/Cr, and Lip/Cr ratios caused by the indicated stimuli. Data are presented as mean ± SD (n=6 per group). ^*P<0.05 vs. Sham; ^#P<0.05 vs. HSR iCORM-3. CORM, carbon monoxide-releasing molecule; HSR, hemorrhage shock and resuscitation; iCORM-3, inactive CORM-3; NAA, N-acetylaspartate; mI, myoinositol; Lip, lipid; Cr, creatinine.