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. 2020 Jan 27;45(4):1141–1149. doi: 10.3892/ijmm.2020.4477

Figure 3.

Figure 3

Predicted functional network between the differentially expressed microRNAs following APC or IPC and the related cell-survival pathway using IPA. This figure represents a simplified network estimated by IPA drawn using an IPA drawing tool. Some of the microRNAs affected by APC or IPC, including miR-17-3p, miR-19a, miR-27a and miR-34a, were estimated to be associated with the substances 'TP53' and 'Akt'. Solid lines represent direct interactions and dashed lines represent indirect interactions. APC, anesthetic preconditioning; IPC, ischemic preconditioning; miR, microRNA; Akt, protein kinase B; IPA, ingenuity pathway analysis.