Conventional and advanced MRI features useful for differentiating between nCET and edema

nCET	Edema
Conventional MRI features
Gray matter involvement	Spares the gray matter
Eccentric	Relatively concentric around enhancing lesions
Relatively mild FLAIR and T2 hyperintensity	More marked FLAIR and T2 hyperintensity
Focal parenchymal expansion	More diffuse mass effect if marked edema
Advanced MRI sequences
Relative diffusion restriction	Facilitated diffusion
Choline elevation, NAA depletion	Normal MRS findings
Elevated rCBV around CET	rCBV elevation confined to CET

Note:—rCBV indicates relative cerebral blood volume.