Skip to main content
. 2019 Dec 27;214(3):635–649. doi: 10.1534/genetics.119.302740

Table 1. Genetic analysis of C. neoformans heterozygous mutants for the MATα and MATa ribosomal proteins Rpl39 and Rpl22.

Genotype Strain Protein function Germinated basidiospores/ dissected basidiospores NAT-R progeny/ basidiospore germinated Phenotype
RPL39α/rpl39aΔ GI229 Large Subunit Ribosomal Protein L39 31/80 – 38.7% 0/31 Inviable
RPL39a/rpl39αΔ GI233 29/70 – 41.4% 0/29 Inviable
RPL22α/rpl22aΔ GI56 Large Subunit Ribosomal Protein L22 23/63 – 36.5% 1/23a Inviable
RPL22a/rpl22αΔ GI81 28/72 – 38.8% 0/28 Inviable
a

The NAT-R progeny obtained is likely aneuploid for chromosome 5, because PCR confirmed the presence of the RPL22α allele and the mutated copy of the RPL22a.