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(A to F) Graphical representation of the predicted metabolic flux redistribution when overexpressing the NADH kinase in the cytosol (A to C) or mitochondria (D to F). Cells were grown in glycerol (A and D), glucose under normoxic conditions (B and E), and glucose under hypoxia (C and F). Blue, black, and red lines denote reactions with decreased, unchanged, and increased metabolic fluxes, respectively.
