Table 3.

Odds ratio (OR) and 95% confidence interval (CI) for documented grade 3-5 chemotherapy-related toxicity associated with social support

	No toxicity	Any grade 3-5 toxicity			By toxicity type
					Hematological alone			Non-hematological alone			Both
	N	N	OR (95% CI)	P value	N	OR (95% CI)	P value	N	OR (95% CI)	P value	N	OR (95% CI)	P value
Univariate analysis
Social support
Good	167	201	1.00		34	1.00		105	1.00		62	1.00
Poor	67	63	0.78 (0.52-1.17)	0.23	15	1.10 (0.56-2.15)	0.78	29	0.69 (0.42-1.13)	0.14	19	0.76 (0.43-1.37)	0.37
Tangible social support
Good	167	197	1.00		33	1.00		101	1.00		63	1.00
Poor	67	67	0.85 (0.57-1.26)	0.41	16	1.21 (0.62-2.34)	0.57	33	0.81 (0.50-1.32)	0.41	18	0.71 (0.39-1.29)	0.26
Emotional/informational support
Good	169	194	1.00		36	1.00		100	1.00		58	1.00
Poor	65	70	0.94 (0.63-1.39)	0.75	13	0.94 (0.47-1.88)	0.86	34	0.88 (0.55-1.43)	0.62	23	1.03 (0.59-1.81)	0.92
Multivariate analysis*
Social support
Good	156	191	1.00		31	1.00		101	1.00		59	1.00
Poor	61	54	0.58 (0.36-0.92)	0.02	14	0.94 (0.45-1.94)	0.86	25	0.52 (0.30-0.91)	0.02	15	0.49 (0.25-0.97)	0.04
Tangible social support
Good	159	187	1.00		32	1.00		97	1.00		58	1.00
Poor	58	58	0.69 (0.44-1.10)	0.12	13	0.91 (0.44-1.91)	0.81	29	0.68 (0.40-1.17)	0.17	16	0.58 (0.30-1.13)	0.11
Emotional/Informational support
Good	158	184	1.00		33	1.00		96	1.00		55	1.00
Poor	59	61	0.77 (0.49-1.21)	0.25	12	0.86 (0.41-1.81)	0.68	30	0.74 (0.44-1.26)	0.27	19	0.77 (0.41-1.45)	0.41

^*Adjustment for CARG Toxicity Risk Group (low, medium, and high).