Table 1.
Sociodemographic, Oncologic, and Psychosocial Characteristics of the Study Cohort (N = 68).
| Characteristic | Median (IQR) or n (%) |
|---|---|
| Age, y | 63 (53–72.25) |
| Sex | |
| Female | 25 (37) |
| Male | 43 (63) |
| Race | |
| White | 55 (81) |
| African American | 11 (16) |
| Other | 2 (3) |
| Marital status | |
| Married/current partner | 38 (56) |
| Single/separated/divorced/widowed | 30 (44) |
| Body mass index | |
| Underweight | 3 (4) |
| Normal weight | 26 (38) |
| Overweight/Obese | 39 (57) |
| Preoperative mood disorder diagnosis | |
| No | 45 (66) |
| Yes | 23 (34) |
| Preoperative psychiatric medication | |
| No | 45 (66) |
| Yes | 23 (34) |
| Preoperative hypothyroidism | |
| No | 53 (78) |
| Yes | l5 (22) |
| Shame and stigma scale scorea | 16 (10–25) |
| PROMIS SF 4a score | |
| Anxietyb | 10 (7–13) |
| Depressionb | 6 (4–10) |
| Social isolation | 4 (4–9) |
| Tumor location and histology | |
| Oral cavity SCC | 37 (54) |
| Oropharynx SCC/SCC of unknown primary | 8(12) |
| Larynx/hypopharynx SCC | 9(13) |
| Facial cutaneous malignancy | 14(21) |
| pl6 status (oropharynx cases only) | |
| Negative | 3 (38) |
| Positive | 5 (63) |
| AJCC pathologic T classification | |
| 0-2 | 32 (47) |
| 3-4b | 36 (53) |
| Ablative surgeryc | |
| Mandibulectomy | 13(19) |
| Glossectomy | 37 (54) |
| Maxillectomy | 5 (7) |
| Radical tonsillectomy/pharyngectomy | 5 (7) |
| Total laryngectomy | 6 (9) |
| Skin/soft tissue resection and/or parotidectomy | 18 (26) |
| Neck dissection | 60 (88) |
| Other | 6 (9) |
| Reconstructive surgery | |
| None or dermal substitute | 17 (25) |
| Regional flap | 6 (9) |
| Microvascular free flap | 45 (66) |
| Osseous microvascular free flap reconstruction | |
| No | 56 (83) |
| Yes | 12 (18) |
| Adjuvant therapy | |
| None | 26 (41) |
| Radiation | 23 (36) |
| Chemoradiationd | 15 (23) |
Abbreviations: AJCC, American Joint Committee on Cancer; IQR, Interquartile range; PROMIS SF, Patient-Reported Outcomes Measurement Information System Short Form; SCC, squamous cell carcinoma.
a
n = 65 due to missing data (n = 3).
b
n = 67 due to missing data (n = 1).
c
n > 68 as patients may belong to > 1 category.
d
n = 64 due to mortality prior to adjuvant therapy (n = 3) and lost to follow-up (n = 1).