Table 3.
Stratified Analysis of Risk, Risk Difference, and Relative Risk of Study Outcomes at 1-Year Post-AMI for Outpatient Cardiac Rehabilitation Initiators verses Non-Initiators
| CR Non-Initiators % Risk (95% CI) | CR Initiators % Risk (95% CI) | Risk Difference (95% CI) | Risk Ratio (95% CI) | |
|---|---|---|---|---|
| AMI | ||||
| Age Group | ||||
| 65-74, yr | 4.6 (4.2 - 5.0) | 3.7 (2.8 - 4.9) | −.8 (−1.4 to −.0) | .82 (.66 - 1.00) |
| 75-84, yr | 5.8 (5.4 - 6.2) | 4.7 (3.4 - 6.2) | −1.1 (−2.1 to −.0) | .81 (.62 - .99) |
| Morbidity Risk | ||||
| Gagne Score < 5 | 4.7 (4.4 - 5.0) | 3.5 (2.8 - 4.1) | −1.2 (−1.6 to −.8) | .74 (.64 - .83) |
| Gagne Score >=5 | 10.6 (9.5 - 11.9) | 11.2 (6.2 - 17.1) | .6 (−3.3 to 5.3) | 1.05 (.65 - 1.44) |
| Day 60 GMT Group | ||||
| 0 | 5.2 (4.1 - 6.3) | 7.0 (1.3 - 15.3) | 1.8 (−2.8 to 9.0) | 1.34 (.33 - 2.43) |
| 1-2 | 5.7 (5.2 - 6.2) | 4.8 (3.0 - 6.5) | −.9 (−2.1 to .3) | .84 (.59, - 1.05) |
| 3-4 | 5.0 (4.7 - 5.4) | 3.8 (2.9 - 4.5) | −1.3 (−1.8 to −.9) | .75 (.62 - .84) |
| MACE | ||||
| Age Group | ||||
| 65-74 yr | 15.4 (14.8 - 16.0) | 13.6 (12.0 - 15.4) | −1.8 (−2.8 to −.6) | .88 (.81 - .96) |
| 75-84 yr | 20.0 (19.2 - 20.9) | 18.0 (15.6 - 21.3) | −2.0 (−3.6 to .4) | .90 (.81 - 1.02) |
| Morbidity Risk | ||||
| Gagne Score < 5 | 16.3 (15.8 - 16.8) | 13.5 (12.6 - 14.7) | −2.7 (−3.2 to −2.1) | .83 (.80 - .88) |
| Gagne Score >=5 | 37.9 (35.9 - 39.9) | 36.1 (26.4 - 45.7) | −1.7 (−9.5 to 5.8) | .95 (.74 - 1.15) |
| Day 60 GMT Group | ||||
| 0 | 20.0 (18.0 - 22.0) | 21.5 (12.8 - 30.7) | 1.5 (−5.1 to 8.7) | 1.08 (.71 - 1.40) |
| 1-2 | 19.1 (18.1 - 19.9) | 17.1 (14.7 - 19.6) | −2.0 (−3.4 to −.3) | .90 (.81 - .98) |
| 3-4 | 17.4 (16.8, 18.0) | 14.6 (12.7 - 16.5) | −2.8 (−4.1 to −1.5) | .84 (.76 - .92) |
| All-Cause Admission | ||||
| Age Group | ||||
| 65-74 yr | 29.9 (29.0 - 30.9) | 28.7 (26.7 - 31.3) | −1.2 (−2.3 to .4) | .96 (.92 - 1.01) |
| 75-84 yr | 35.7 (34.6 - 36.6) | 32.6 (28.9 - 35.4) | −3.0 (−5.7 to −1.2) | .92 (.84 - .97) |
| Morbidity Risk | ||||
| Gagne Score < 5 | 31.3 (30.7 - 31.9) | 27.7 (26.0 - 28.9) | −3.6 (−4.7 to −3.0) | .89 (.85 - .91) |
| Gagne Score >=5 | 56.6 (54.0 - 58.8) | 57.0 (46.9 - 65.8) | .4 (−7.1 to 7.0) | 1.01 (.87 - 1.12) |
| Day 60 GMT Group | ||||
| 0 | 33.0 (30.1 - 36.0) | 39.7 (28.5 - 51.4) | 6.7 (−1.6 to 15.4) | 1.20 ( .95 - 1.43) |
| 1-2 | 34.1 (32.5 - 35.4) | 31.8 (28.4 - 35.0) | −2.3 (−4.1 to −.4) | .93 (.87 - .99) |
| 3-4 | 32.8 (32.0 - 33.6) | 29.1 (26.8 - 31.1) | −3.7 (−5.2 to −2.5) | .89 (.84 - .93) |
Abbreviations: AMI – acute myocardial infarction; GMT, guideline-directed medical therapy; MACE, major cardiovascular event (AMI, angina, heart failure, or stroke);