Extended Data Table 1.

The number of DBSs is proportional to the number of SBSs, with few exceptions

The exceptions are colorectal adenocarcinoma (Colorect–AdenoCA), lung adenocarcinoma (Lung–AdenoCA), lung squamous cell carcinoma (Lung–SCC) and skin–melanoma, as analysed by the following linear regression (computed by an R function call): glm(DBS.count ~ SBS.count + Cancer.Type). This function call fits a model in which the number of DBSs depends linearly on the number of SBSs and on the cancer type. P values associated with the coefficients are two-sided.