Table 6.
Factors associated and attributable fraction (AF) with nutritional recovery (n 4163) among all children (n 4958) included in Optimising treatment for acute MAlnutrition (OptiMA) protocol, Yako district, Burkina Faso, 2017*
(Numbers and percentages; hazard ratios (HR) and 95 % confidence intervals)
| n/N | % | Univariate analysis | Multivariate analysis (n 4201) | AF | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Crude HR | 95 % CI | P | Adjusted HR | 95 % CI | P | AF | 95 % CI | |||
| Child socio-demographic characteristics | ||||||||||
| Age category (n 4958) | ||||||||||
| <24 months | 3376/4077 | 82·8 | 1 | 1 | <0·0001 | |||||
| ≥24 months | 787/881 | 89·3 | 1·61 | 1·48, 1·75 | 1·61 | 1·48, 1·75 | 9·7 | 8·4, 13·1 | ||
| Sex (n 4941) | ||||||||||
| Female | 2381/2884 | 82·6 | 1 | <0·0001 | 1 | <0·0001 | ||||
| Male | 1768/2057 | 86 | 1·21 | 1·14, 1·29 | 1·21 | 1·13, 1·29 | 8·1 | 4·0, 10·4 | ||
| Mode of referral (n 4845) | ||||||||||
| Outpatient consultation | 1869/2253 | 83 | 1 | 0·05 | ||||||
| Community agent | 1619/1904 | 85 | 1·04 | 0·97, 1·11 | ||||||
| Mothers screening | 545/628 | 86·8 | 0·9 | 0·81, 1·01 | ||||||
| Inpatient consultation | 49/60 | 81·7 | 1·15 | 0·86 , 1·53 | ||||||
| Distance to the health centre (km) (n 4703) | ||||||||||
| ≥10 | 376/447 | 84·1 | 1 | <0·0001 | 1 | <0·001 | ||||
| <10 | 3585/4256 | 84·2 | 1·28 | 1·13, 1·45 | 1·25 | 1·11, 1·42 | 18·1 | 11·0, 24·8 | ||
| Mother’s characteristics at admission | ||||||||||
| Mother’s status (n 4873) | ||||||||||
| Death | 53/67 | 79·1 | 1 | 0·04 | 1 | 0·03 | ||||
| Alive | 4047/4806 | 84·2 | 1·36 | 1·02, 1·81 | 1·39 | 1·02, 1·89 | 26·9 | 9·5, 40·8 | ||
| No. of siblings (n 4697) | ||||||||||
| 0 | 13/18 | 72·2 | 1 | 0·9 | ||||||
| 1–4 | 2267/2711 | 83·6 | 0·97 | 0·57, 1·63 | ||||||
| 4–12 | 1683/1968 | 85·5 | 0·98 | 0·58, 1·66 | ||||||
| Breast-feeding (n 4512) | ||||||||||
| No | 597/692 | 86·3 | 1 | <0·0001 | ||||||
| Yes | 3226/3820 | 84·5 | 0·76 | 0·70, 0·83 | ||||||
| MUAC training | ||||||||||
| No | 881/1111 | 79·3 | 1 | 0·02 | 1 | 0·05 | ||||
| Yes | 3201/3733 | 85·7 | 1·10 | 1·01, 1·20 | 1·09 | 1·0, 1·19 | 6·7 | 1·8, 12·0 | ||
| Malaria prevention | ||||||||||
| At least one RDT positive | ||||||||||
| Yes | 1160/1354 | 85·7 | 1 | 0·2 | ||||||
| No | 2916/3504 | 83·2 | 1·05 | 0·98, 1·13 | ||||||
| SMC† at admission | ||||||||||
| Included out of SMC campaign‡ | 2998/3350 | 84·5 | 1 | 0·002 | 1 | 0·001 | ||||
| SMC campaign‡ eligible and received | 258/305 | 84·6 | 1·09 | 0·96, 1·25 | 1·06 | 0·93, 1·22 | 6·6‡ | 2·5, 12·7 | ||
| SMC campaign‡ eligible and not received | 872/1052 | 82·9 | 0·89 | 0·82, 0·96 | 0·87 | 0·81, 0·94 | ||||
MUAC, mid upper arm circumference; RDT, rapid diagnostic tests; SMC, seasonal malaria chemoprevention.
Shared frailty model with a random effect on health centres censoring at 12 weeks of inclusion in the programme.
SMC campaign period from July to October 2017.
SMC at admission was combined in two categories ‘included out of SMC campaign’ and ‘included during SMC campaign’, the reference chosen for the AF calculation was ‘included during SMC campaign’.