Table 2.
The associations between the SNP rs1516569 of GRM7 and schizophrenia.
Study | Chr | BP | SNP | A1 | A2 | OR | P |
---|---|---|---|---|---|---|---|
GWAS1 of CSCG19 (746 cases and 1599 controls) | 3 | 7004873 | rs1516569 | C | G | 1.06 | 0.66 |
GWAS2 of CSCG19 (1595 cases and 1447 controls) | 3 | 7004873 | rs1516569 | C | G | 1.11 | 0.12 |
PGC-Asian20 (22,778 cases and 35,362 controls) | 3 | 7004873 | rs1516569 | C | G | 0.97 | 0.72 |
PGC-Clozuk18 (40,675 cases and 64,643 controls) | 3 | 7004873 | rs1516569 | C | G | 0.95 | 7.63E-05 |
Meta-analysis 65,794 cases and 103,051 controls | 3 | 7004873 | rs1516569 | C | G | 0.85 | 3.47E-04 |
GWAS1 and GWAS2 of CSCG were not included in PGC Asian project. Therefore, we performed a meta-analysis of four GWAS datasets.
CHR chromosome, SNP single nucleotide polymorphism, BP base position, A1/A2 minor allele/major allele, OR odds ratio.