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. 2020 Mar 3;10:3951. doi: 10.1038/s41598-020-59043-x

Table 1.

Gene ontology analysis of ethanol-dysregulated genes.

Category Term Count p-value
GOTERM_BP_DIRECT GO:0006355~regulation of transcription, DNA-templated 45 0.016
GOTERM_BP_DIRECT GO:0001756~somitogenesis 9 0.001
GOTERM_BP_DIRECT GO:0005975~carbohydrate metabolic process 9 0.062
GOTERM_BP_DIRECT GO:0031101~fin regeneration 8 0.001
GOTERM_BP_DIRECT GO:0009953~dorsal/ventral pattern formation 7 0.050
GOTERM_BP_DIRECT GO:0016055~Wnt signaling pathway 7 0.088
GOTERM_BP_DIRECT GO:0007219~Notch signaling pathway 6 0.006
GOTERM_BP_DIRECT GO:0009952~anterior/posterior pattern specification 6 0.007
GOTERM_BP_DIRECT GO:0007018~microtubule-based movement 6 0.042
GOTERM_BP_DIRECT GO:0000278~mitotic cell cycle 6 0.046
GOTERM_BP_DIRECT GO:0001889~liver development 6 0.059
GOTERM_BP_DIRECT GO:0021549~cerebellum development 5 0.001
GOTERM_BP_DIRECT GO:0016337~single organismal cell-cell adhesion 5 0.030
KEGG_PATHWAY dre00561:Glycerolipid metabolism 5 0.066
KEGG_PATHWAY dre03320:PPAR signaling pathway 5 0.094
GOTERM_BP_DIRECT GO:0048384~retinoic acid receptor signaling pathway 4 0.004
GOTERM_BP_DIRECT GO:0001878~response to yeast 4 0.019
GOTERM_BP_DIRECT GO:0018279~protein N-linked glycosylation via asparagine 4 0.041
GOTERM_BP_DIRECT GO:0006310~DNA recombination 4 0.063
GOTERM_BP_DIRECT GO:0001757~somite specification 3 0.038
GOTERM_BP_DIRECT GO:0061386~closure of optic fissure 3 0.043
GOTERM_BP_DIRECT GO:0009948~anterior/posterior axis specification 3 0.062
GOTERM_BP_DIRECT GO:0001574~ganglioside biosynthetic process 3 0.076
GOTERM_BP_DIRECT GO:0006094~gluconeogenesis 3 0.076
GOTERM_BP_DIRECT GO:0036342~post-anal tail morphogenesis 3 0.098
GOTERM_BP_DIRECT GO:0071539~protein localization to centrosome 2 0.070
GOTERM_BP_DIRECT GO:0045814~negative regulation of gene expression, epigenetic 2 0.071
GOTERM_BP_DIRECT GO:0061056~sclerotome development 2 0.093
REACTOME_PATHWAY Polyamine metabolic process:R-DRE-351202:R-DRE-351202 2 0.099

Category refers to the original database where the terms orient; term refers to the enriched term associated to the gene list; count refers to the total number of differentially expressed genes annotated to a given gene ontology term; the smaller the p-value, the more enriched the term.