Table 1.

Single-nucleotide variants (SNVs) and indels in the differentiated lines based on RNAseq data.

No.	Layer	Control	Case	Total SNPs	>20% of alternative allelic frequency	protein_coding	functional SNPs	# of genes	#Corr. w/expression
1	Neuron	p20-iPS	p40-iPS	1,407	712	452	24	23	0
2		p20-iPS	p20- rosettes	1,679	850	491	20	20	0
3		p20-iPS	p20-Neuron	1,010	504	310	18	18	0
4		p40-iPS	p40- rosettes	1,367	699	418	16	16	0
5		p40-iPS	P40-Neuron	1,043	548	356	17	17	0
6	Heart	p25-iPS	p47-iPS	1,145	544	303	24	19	0
7		p25-iPS	p25-Stage1	1,065	441	288	7	7	0
8		p25-iPS	p25-Stage2	1,083	472	304	14	13	0
9		p25-iPS	p25-Stage3	1,261	659	396	20	17	0
10		p47-iPS	p47-Stage1	1,362	699	397	24	21	0
11		p47-iPS	p47-Stage2	1,014	476	304	31	28	0
12		p47-iPS	p47-Stage3	1,671	1,097	642	19	17	0
13	Liver	p20-iPS	p37-iPS	1,584	829	494	24	22	0
14		p20-iPS	p20-DE	1,198	562	358	38	37	0
15		p20-iPS	p20-HE	827	406	289	26	25	0
16		p20-iPS	P20-HLC	1,244	626	392	29	27	0
17		p37-iPS	p37-DE	1,616	909	572	37	34	0
18		p37-iPS	p37-HE	1,148	619	430	29	27	0
19		p37-iPS	p37-HLC	1,509	823	465	34	33	0