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. 2019 Dec 19;122(5):640–647. doi: 10.1038/s41416-019-0697-x

Fig. 4. PD-L1, but not NBS1, expression correlates with the knockdown of STAT1 or STAT3 expression in both chemoresistant and chemosensitive cell lines.

Fig. 4

PD-L1 but not NBS1 was qualitatively downregulated in both JHU006 and JHU020 cell lines 48 h after siRNA-mediated knockdown of STAT1 or STAT3. The quantitative data demonstrate that there were statistically significant differences in PD-L1 expression in both cell lines between either the siRNA-STAT1- or siRNA-STAT3-treated samples and the control sample (*P < 0.05). The expression of NBS1 was unchanged in both cell lines following the application of siRNA-STAT1 or siRNA-STAT3. The statistics represent the standard errors of the means from three separate experiments. The western blots are cropped in order to improve clarity.