Fig. 6. PD-L1 and NBS1 knockdown sensitises JHU006 HNSCC cells in vivo.

a The change in the tumour volume following a range of treatments was followed over time. b The tumour volumes were measured pre-treatment (white) and post-treatment (black), at 15 days after tumour establishment. The addition of cisplatin alone resulted in a large decrease in tumour size. This decrease was enhanced by the application of adenoviruses. It was noticeable that the mice that received the adenoviral mixture experienced the largest decrease in tumour size (*P < 0.05). The statistics represent the standard errors of the means from three separate experiments.