Figure 3.

Young adult crawling differences due to ryanodine receptor (RyR) variants. Amplitudes and wavelengths of the crawling wave form (A) were extracted from 1 min long, 25 frames per second, video recordings of 20–30 individual young adults, along with worm length and wave frequency. Worm length (B), maximum amplitude versus wavelength (C), and maximum amplitude versus frequency (D) for RyR variant strains, labelled by the human variant they correspond to, along with the N2 wild type and the CB540 unc-68(e540) null mutant, were compared. Maximum amplitude and wavelength were normalized for worm length. Boxes indicate the median and interquartile range, with whiskers to the 10–90 percentile, outliers as dots, and + to indicate the mean (B). Mean and SEM are indicated, although SEM is very small for frequency and for normalized maximum amplitude and wavelength (C, D).