Skip to main content
. 2020 Mar 3;10:82. doi: 10.1038/s41398-020-0750-9

Table 1.

Sample descriptives.

ASD Females ASD Males NT Females NT Males Females ASD vs. NT Males ASD vs. NT ASD Female vs. Male NT Female vs. Male
Age 13.84 13.50 13.49 13.17 0.59 0.50 0.53 0.60
Full IQ 97.91 105.24 112.97 106.26 0.001b 0.72 0.08 0.03a
Nonverbal IQ 99.53 105.65 110.82 105.32 0.009b 0.92 0.12 0.11
Verbal IQ 101.16 103.73 111.18 107.09 0.018a 0.23 0.50 0.19
ADOS social 7.97 9.70 0.05a
ADOS repetitive behavior 2.06 2.29 0.57
ADOS severity score 6.13 7.02 0.10
ADI social 19.09 20.11 0.41
ADI Communication 15.77 16.30 0.64
ADI repetitive behavior 6.00 6.78 0.21
Mean relative motion 0.12 0.08 0.09 0.08 0.16 0.27 0.02a 0.10
Mean volumes scrubbed 14.97 2.81 8.58 2.97 0.21 0.89 0.003b 0.07
Mean OXTR risk variants 3.44 3.30 3.45 3.12 0.94 0.47 0.58 0.19
Subjects with ≥1 risk allele
 rs1042778 28 30 27 23 0.53 0.19 0.47 0.18
 rs2254298 6 7 8 9 0.59 0.45 0.99 0.83
 rs53576 21 20 21 12 0.87 0.11 0.33 0.02a
 rs237887 28 27 25 29 0.22 0.20 0.14 0.32
Self-reported ethnicity
 Asian 2 2 3 3 0.67 0.57 0.88 0.97
 Black/African American 0 2 3 6 0.08 0.10 0.18 0.31
 Other/Mixed 4 4 5 2 0.76 0.46 0.83 0.22
 White 26 25 22 19 0.18 0.31 0.20 0.37

Mean values and p-values derived from two-tailed independent samples t-tests or chi-squared tests. ap < 0.05; bp < 0.01.

ASD autism spectrum disorder, NT neurotypical, IQ intelligence quotient, ADOS Autism diagnostic observation schedule, ADI Autism Diagnostic interview, OXTR oxytocin receptor gene.