Table 2.
Individual edge effect estimates for the TC and TC-PA structural equation models
| Outcome node/parent node (edge) | Cohort 1 (no diabetes/prediabetes) |
Cohort 2 (diabetes) | ||||
|---|---|---|---|---|---|---|
| β | β SE | p value | β | β SE | p value | |
| TC model | ||||||
| OGIS/ | ||||||
| LF (is1) | −0.23 | 0.04 | <0.001 | −0.11 | 0.06 | 0.09 |
| LF/ | ||||||
| FI (lf1) | 0.41 | 0.04 | <0.001 | 0.44 | 0.05 | <0.001 |
| FI/ | ||||||
| FG (fi1) | −0.06 | 0.03 | 0.05 | −0.25 | 0.06 | <0.001 |
| IS (fi2) | −0.70 | 0.03 | <0.001 | −0.70 | 0.06 | <0.001 |
| FG/ | ||||||
| IS (fg1) | −0.67 | 0.03 | <0.001 | −0.73 | 0.03 | <0.001 |
| GS (fg2) | −0.26 | 0.03 | <0.001 | −0.31 | 0.03 | <0.001 |
| TG/ | ||||||
| IS (tg1) | −0.31 | 0.03 | <0.001 | −0.34 | 0.05 | <0.001 |
| LF (tg2) | 0.22 | 0.03 | <0.001 | 0.13 | 0.05 | 0.006 |
| PF/ | ||||||
| TG (pf1) | 0.14 | 0.03 | <0.001 | 0.01 | 0.05 | 0.886 |
| GS/ | ||||||
| PF (gs1) | −0.05 | 0.04 | 0.185 | <0.01 | 0.05 | 0.967 |
| IS (gs2) | −0.21 | 0.03 | <0.001 | 0.02 | 0.05 | 0.63 |
| PG/ | ||||||
| IS (pg1) | −0.58 | 0.03 | <0.001 | −0.67 | 0.03 | <0.001 |
| GS (pg2) | −0.17 | 0.03 | <0.001 | −0.38 | 0.03 | <0.001 |
| TC-PA model | ||||||
| IS/ | ||||||
| PA (is2) | 0.30 | 0.04 | <0.001 | 0.21 | 0.05 | <0.001 |
| LF (is1) | −0.20 | 0.04 | <0.001 | −0.12 | 0.07 | 0.065 |
| LF/ | ||||||
| PA (lf2) | −0.04 | 0.04 | 0.234 | −0.04 | 0.05 | 0.447 |
| FI (lf1) | 0.41 | 0.04 | <0.001 | 0.44 | 0.05 | <0.001 |
| FI/ | ||||||
| PA (fi3) | −0.12 | 0.03 | <0.001 | −0.16 | 0.05 | 0.001 |
| FG (fi1) | −0.04 | 0.03 | 0.265 | −0.23 | 0.07 | <0.001 |
| IS (fi2) | −0.64 | 0.04 | <0.001 | −0.64 | 0.07 | <0.001 |
| FG/ | ||||||
| PA (fg3) | 0.11 | 0.03 | 0.001 | 0.06 | 0.03 | 0.061 |
| IS (fg1) | −0.70 | 0.03 | <0.001 | −0.73 | 0.03 | <0.001 |
| GS (fg2) | −0.26 | 0.03 | <0.001 | −0.28 | 0.03 | <0.001 |
| TG/ | ||||||
| PA (tg3) | −0.13 | 0.04 | <0.001 | −0.13 | 0.05 | 0.012 |
| OGIS (tg1) | −0.26 | 0.04 | <0.001 | −0.30 | 0.05 | <0.001 |
| LF (tg2) | 0.22 | 0.04 | <0.001 | 0.16 | 0.05 | 0.002 |
| PF/ | ||||||
| PA (pf2) | −0.06 | 0.03 | 0.067 | −0.01 | 0.06 | 0.809 |
| TG (pf1) | 0.14 | 0.03 | <0.001 | −0.01 | 0.05 | 0.819 |
| GS/ | ||||||
| PA (gs3) | −0.05 | 0.04 | 0.212 | −0.12 | 0.06 | 0.032 |
| PF (gs1) | −0.05 | 0.05 | 0.314 | 0.01 | 0.05 | 0.835 |
| IS (gs2) | −0.18 | 0.04 | <0.001 | 0.02 | 0.05 | 0.696 |
| PG/ | ||||||
| PA (pg3) | −0.04 | 0.03 | 0.194 | −0.05 | 0.04 | 0.162 |
| IS (pg1) | −0.56 | 0.03 | <0.001 | −0.67 | 0.03 | <0.001 |
| GS (pg2) | −0.17 | 0.03 | <0.001 | −0.39 | 0.03 | <0.001 |
All continuous variables were normally transformed and adjusted for age, sex, metformin treatment (cohort 2), study centre, total energy intake and carbohydrate, fat and protein intake
See Text box for node and edge abbreviations