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. 2020 Feb 26;11:254. doi: 10.3389/fimmu.2020.00254

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Copyright © 2020 Garcia-Flores, Romero, Furcron, Levenson, Galaz, Zou, Hassan, Hsu, Olson, Metz and Gomez-Lopez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neonatal outcomes of prenatal maternal stress across generations. (A) Experimental design of neonates born to stressed dams across generations. (B) Rate of neonatal mortality at birth in each generation (control n = 10; F1-S n = 19; F2-SS n = 19; F3-SSS n = 30). (C) Growth trajectory of neonates in the first 3 weeks after birth (control n = 5 litters; F1-S n = 8 litters; F2-SS n = 2 litters; F3-SSS n = 21 litters). Data are presented as mean ± standard error of the mean.