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. 2020 Mar 3;11(3):167. doi: 10.1038/s41419-020-2356-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Potential MYC binding sites were predicted on HMGA1P6 promoter region. b ChIP-qPCR was conducted to analyze the binding sites of MYC on promoter region of HMGA1P6 in HEY cells. c Luciferase activity was measured in HEK293T cells co-transfected with MYC overexpression plasmids, siRNAs and pGL4 plasmid containing HMGA1P6 promotor region (wild type and mutant). d, e MYC, HMGA1P6, and HMGA1/2 expression was measured in cells with MYC overexpression or knockdown. Data are presented as means ± S.D. *p < 0.05, **p < 0.01.