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. 2020 Mar 3;3:94. doi: 10.1038/s42003-020-0827-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, b Expression and distribution of F-actin and β-catenin in wild type and Migf2bp3 embryos at 2-, 4-, and 8-cell stages. The F-actin and β-catenin were enriched in mature and apparent cleavage furrow (triangle). The inset showed a zoom-in of the boxed region at each stage. Zoomed-out scale bar = 100 μm; zoomed-in scale bar = 50 μm. a Migf2bp3 embryos at 4-cell stage did neither exhibit intact adhesion junction of F-actin cables nor form the mature furrow (white arrow). b Migf2bp3 embryos exhibited reduced expression of β-catenin (white arrows) and did not form intact cell adhesion junction with defective furrow (white bracket). c Double localization of F-actin (green fluorescence) and CG (red fluorescence). The inset showed a zoom-in of the boxed region at each stage. Zoomed-out scale bar = 100 μm; zoomed-in scale bar = 50 μm.