TABLE 3.

PPARGC1A methylation level among different SNPs genotypes.

SNPs genotypes		rs2970848			rs2970870			rs6821591
		AA	AG + GG	P	AG	AA + GG	P	TT	CT + CC	P
Mean PPARGC1A methylation level (%)	PD	7.29 ± 1.59	7.02 ± 1.94	0.473	7.30 ± 1.76	6.98 ± 1.72	0.398	7.27 ± 1.64	7.12 ± 1.80	0.688
	Con	6.50 ± 1.30	6.23 ± 1.27	0.342	6.43 ± 1.36	6.28 ± 1.20	0.610	6.52 ± 1.39	6.18 ± 1.15	0.236
	Total	6.94 ± 1.52	6.61 ± 1.66	0.167	6.91 ± 1.64	6.62 ± 1.50	0.239	6.85 ± 1.54	6.74 ± 1.63	0.641
CpG_1	PD	3.71 ± 2.26	3.24 ± 2.10	0.313	3.68 ± 2.28	3.24 ± 2.05	0.356	3.52 ± 2.29	3.51 ± 2.16	0.989
	Con	2.65 ± 1.78	2.66 ± 1.64	0.982	3.00 ± 1.80	2.22 ± 1.48	0.040	2.43 ± 1.82	2.90 ± 1.54	0.216
	Total	3.25 ± 2.12	2.94 ± 1.88	0.312	3.38 ± 2.10	2.71 ± 1.84	0.034	2.91 ± 2.10	3.26 ± 1.94	0.256
CpG_13.14	PD	7.73 ± 1.84	6.71 ± 2.10	0.016	7.27 ± 2.06	7.35 ± 1.95	0.847	7.24 ± 1.77	7.33 ± 2.15	0.837
	Con	6.67 ± 1.73	6.59 ± 1.76	0.818	6.84 ± 1.76	6.36 ± 1.69	0.215	6.95 ± 1.74	6.28 ± 1.69	0.082
	Total	7.27 ± 1.86	6.65 ± 1.92	0.032	7.08 ± 1.93	6.84 ± 1.88	0.427	7.08 ± 1.75	6.91 ± 2.03	0.556
CpG_17.18	PD	9.44 ± 6.82	9.95 ± 8.31	0.752	10.46 ± 8.53	8.32 ± 5.03	0.187	10.12 ± 7.68	9.39 ± 7.36	0.654
	Con	4.60 ± 4.28	6.07 ± 4.33	0.128	5.78 ± 5.06	4.81 ± 3.23	0.320	5.40 ± 4.24	5.28 ± 4.51	0.900
	Total	7.34 ± 6.30	7.94 ± 6.80	0.550	8.38 ± 7.53	6.51 ± 4.53	0.066	7.48 ± 6.40	7.72 ± 6.64	0.813
CpG_20	PD	2.00 ± 1.62	2.47 ± 2.66	0.298	2.43 ± 2.47	1.82 ± 1.31	0.191	1.82 ± 1.47	2.42 ± 2.41	0.195
	Con	1.50 ± 1.41	1.56 ± 1.34	0.843	1.64 ± 1.50	1.40 ± 1.20	0.408	1.33 ± 1.41	1.74 ± 1.31	0.180
	Total	1.78 ± 1.55	2.00 ± 2.12	0.440	2.08 ± 2.12	1.60 ± 1.27	0.092	1.55 ± 1.45	2.15 ± 2.05	0.033

Significant results are highlighted in bold. P-value for Mann–Whitney U test.