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. 2020 Jan 17;9(1):115–125. doi: 10.1007/s40123-020-00229-x

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© The Author(s) 2020, corrected publication 2021

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Fig. 1 — Brimonidine (a) and timolol (b) concentrations in the aqueous humor after concomitant administration of 0.1% brimonidine tartrate ophthalmic solution (BMD) and 0.5% timolol ophthalmic solution (TIM) in rabbits. TIM (35 µl) was administered 5 min after BMD (35 µl) instillation to one eye of each rabbit. For the other eye of each rabbit, TIM was administered after BMD (35 µl) instillation in succession within 10 s in the non-interval group. Data are presented as mean ± standard deviation (n = 3)