Table 5.

Final logistic regression model for the occurrence of vancomycin-associated acute kidney injury

Parameter	Adjusted odds ratio (95% confidence interval)	p value
No medical insurance	3.451 (1.310–9.090)	0.012
Chronic alcohol abuse	4.710 (1.929–11.499)	0.001
ICU admission within 24 h of vancomycin initiation	4.398 (1.676–11.541)	0.003
Receipt of Gram-negative coverage	2.926 (1.158–7.392)	0.023
Vancomycin durationa	1.143 (1.037–1.260)	0.007

AUC area under the curve, ICU intensive care unit

Overall p value (likelihood ration test) was < 0.001; Hosmer–Lemeshow test p = 0.340; AUC 0.776 (95% CI 0.700–0.851)

^aThe adjusted odds ratio for vancomycin duration reflects the increased likelihood of V-AKI for each one day increase in vancomycin length of therapy