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. 2020 Mar 3;4:5. doi: 10.1038/s41698-020-0110-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a The expression of LINC00263 increased in 473 colon cancer tumor tissues compared to 41 normal tissue in the TCGA database (P < 0.0001). b Comparison of the expression of LINC00263 between 212 female tumor tissue and 235 male tumor tissues (P = 0.04). c–e Kaplan–Meier curves for overall survival rates associated with LINC00263 expression in colon cancers (low expression numbers = 140, high expression numbers = 129) c and females (low expression number = 28, high expression number = 47) d and males (low expression number = 32, high expression number = 58). f The expression of LINC00263 increased in 819 renal cell carcinoma tumor tissues compared to 113 normal tissue in the TCGA database (P < 0.0001). g Comparison of the expression of LINC00263 between 194 female tumor tissue and 396 male tumor tissues (P = 0.003). h–j Kaplan–Meier curves for overall survival rates associated with LINC00263 expression in renal cell carcinoma (low expression numbers = 418, high expression numbers = 399) h and females (low expression number = 155, high expression number = 107) i and males (low expression number = 298, high expression number = 257) j. k The expression of LINC00263 increased in 411 Hepatocellular carcinoma tumor tissues compared to 58 normal tissue in the TCGA database (P = 0.001). l–n Comparison of the expression of LINC00263 between normal tissues and tumor tissues in female (P = 0.08)(l) and in males (P = 0.006) m and between 120 female tumor tissues and 249 male tumor tissues (P = 0.38) n. o, p Kaplan–Meier curves for overall survival rates associated with LINC00263 expression in females (low expression number = 77, high expression number = 44) o and males (low expression number = 66, high expression number = 183) p. q The expression of LINC00263 increased in 499 prostate cancer tumor tissues compared to 52 normal tissue in the TCGA database (P = 0.005). r Kaplan–Meier curves for overall survival rates associated with LINC00263 expression in prostate cancer (low expression number = 247, high expression number = 248). s The expression of LINC00263 increased in 12 ovarian cancer normal tissues compared to 12 tumor tissue in the GEO database (GSE14407) (P = 0.01). t Kaplan–Meier curves for overall survival rates associated with LINC00263 expression in ovarian cancer (low expression number = 174, high expression number = 199). u The expression of LINC00263 increased in 1071 breast cancer tumor tissues compared to 98 normal tissue in the TCGA database (P = 0.007). v Comparison of the expression of LINC00263 between 1059 female tumor tissue and 12 male tumor tissues (P = 0.01). w Kaplan–Meier curves for overall survival rates associated with LINC00263 expression in breast cancer (low expression number = 354, high expression number = 723). Data are shown as the mean ± SEM; n ≥ 3 independent experiments, two-tailed Student’s t-test: ns nonsignificant (P > 0.05), *P < 0.05, **P < 0.01, ***P < 0.001.