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. 2020 Mar 3;11:1168. doi: 10.1038/s41467-020-14962-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, b Total nuclear telomere fluorescence in intestine (a) and liver (b) sections of rapamycin- or control-fed Terc^+/+ and G2 Terc^−/− mice at the endpoint, measured by Q-FISH. a.u.f. arbitrary units of fluorescence. Error bars represent the SE. c Mean telomere fluorescence in white blood cells from mice of both genotypes at 4.5, 6–7, 12–15, and 15–20 months of age, measured by high throughput Q-FISH. Values and error bars represent the mean and SE, respectively. n = number of mice. Statistical significance was determined by one-way Anova with post hoc Tukey test. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s. not significant. Source data are provided as a Source Data file.