Skip to main content
. 2019 Aug 3;33(4):670–677. doi: 10.5713/ajas.19.0463

Figure 1.

Figure 1

(A) Chemical structure of LMT-28. (B) Inhibition of IL-6-induced STAT3 activation by LMT-28. (a) HepG2 cells were treated with IL-6 alone (10 ng/mL) for 1, 5, 10, 30, or 60 min, and phosphorylated-STAT3 (p-STAT3) was detected by Western blotting (WB). (b) HepG2 cells were treated with LMT-28 (1, 3, 10, 30, or 100 μM) for 1 h and then were stimulated for 10 min with IL-6 (10 ng/mL). Cells were collected, lysed, and analyzed for p-STAT3 by WB. α-Tubulin was detected as a loading control. STAT3, signal transducer and activator of transcription factor-3.