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. 2019 Aug 3;33(4):670–677. doi: 10.5713/ajas.19.0463

Figure 2.

Figure 2

Microsomal metabolic stability of LMT-28 in rat and human (A) and MDCK cell permeability of LMT-28 (B). The remaining amount of LMT-28 (1 μM, n = 3) at 10, 30, 60 min after the microsomal incubation at 37°C were plotted in rat (circle) and human (square) microsomes. Accumulative amount of LMT-28 across MDCK cell monolayers were plotted at 30, 60, 90, 120 min after incubation in 12-well Transwell plate for transport study. Each point represents mean±standard deviation. MDCK, Madin-Darby canine kidney.