Table II.
Gene expression of IL-8, MUC2 and LYPD8 classified by sex, location of disease, disease type and presence of recurrence in the lesioned colon of patients with ulcerative colitis.
| Characteristics | IL-8, x10-4 | MUC2, 10-2 | Lypd8, x10-2 |
|---|---|---|---|
| Sex | |||
| Male | 4.07±38.3 | 11.5±24.0a | 3.65±4.24 |
| Female | 2.37±7.26 | 6.53±3.76 | 4.37±5.76 |
| Location | |||
| Pancolitis | 3.05±21.0 | 8.99±23.7 | 4.23±4.51 |
| Left | 16.2±58.5 | 5.92±17.8 | 3.18±6.54 |
| Distal | 3.31±5.26 | 3.02±15.5 | 1.87±1.84 |
| Sub-type | |||
| Single attack only | 3.15±5.91 | 7.11±6.12 | 4.37±4.88 |
| Relapsing | 11.2±28.5 | 35.5±26.6b,c | 3.47±2.75 |
| Chronic | 4.83±60.5 | 4.95±3.20 | 5.26±6.49 |
| Recurrent | 16.5±62.7 | 21.6±20.4 | 1.60±4.86 |
| Non recurrent | 3.24±10.1 | 7.00±21.0 | 4.01±4.80 |
aP<0.05,
bP<0.01 vs. single attack only sub-type;
cP<0.01 vs. chronic sub-type. Data are presented as mean ± standard deviation. IL-8, interleukin-8; MUC2, mucin2; LYPD8, LY6/PLAUR domain containing 8.