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. 2020 Feb 11;12(4):143–152. doi: 10.3892/br.2020.1276

Table I.

Acute phase reactants, associated inflammatory cytokines and references.

A, Positive acute phase reactants
Author, year Reactant Associated cytokines (Refs.)
Sharpe-Timms et al, 2010 Haptoglobin IL1β, IL-6, IL-8, TNF-α, (9)
He et al, 2006 Serum amyloid IL1β, IL-6, IL-8, IL-12, IL-23 (143)
Lu et al, 2015 Fibrinogen IL-6, IL-6, TNF-α, IL-1β, IL-8 (144)
Lazzaro et al, 2014 Ceruloplasmin IL-1β, TNF-α, IFN-l (145)
Martinez Cordero et al, 2008 α-1 acid glycoprotein TNF-α, IL-1, IL-6 (146)
de Serres and Blanco, 2014 α-1 antitrypsin TNF-α, IL-6, IL-1β, IL-8, IL-32 (147)
Haversen et al, 2002 Lactoferrin TNF-α, IL-6, IL-1β, IL-8 (148)
Du Clos, 2000 C-reactive protein IL-6, IL-1a, IL-1β, TNF-α (149)
B, Negative acute phase reactants
Author, year Reactant Associated cytokines (Refs.)
Spadaro et al, 2014 Albumin IL-6, TNF-α (150)
Feelders et al, 1998 Transferrin IL-6, TNF-α, IL1 (151)
Bartalena et al, 1992 Transthyretin IL-6, IL-1, TNF-α (152)

IL, interleukin; TNF, tumor necrosis factor.