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. 2018 Nov 23;85(6):762–772. doi: 10.1093/neuros/nyy449

TABLE 4.

Multivariate Results for 4 Different Outcomes Following LA

Factor Hazard ratio (95% C.I.)a P
PFSb
 TDT-line risk group (favorable vs intermediate vs unfavorable) 2.41 (1.26-4.59) .008
DSPFSc
 TDT-line risk group (favorable vs intermediate vs unfavorable) 18.49 (3.96-86.24) .0002
 Tumor location (lobes vs other) 0.07 (0.01-0.33) .0009
OSb
 Age (<70 vs ≥70) 4.89 (1.27-18.80) .02
 Tumor volume (<11 vs ≥11 cm3) 4.32 (1.16-16.02) .03
DSOSc
 TDT-line risk group (favorable vs intermediate vs unfavorable) 6.30 (2.45-16.23) .0001
 Age (<70 vs ≥70) 10.99 (1.32-91.24) .03
 Gender (Female vs Male) 9.45 (1.10-80.89) .04

PFS: progression-free survival, DSPFS: disease specific progression-free survival, OS: overall survival, DSOS: disease specific overall survival, C.I: confidence interval, TDT-line: thermal damage threshold line

aThe first group listed is the reference; ratios > 1 indicate the risk of death is greater in the second group; ratios < 1 that it is less. For NeuroBlate risk group the (sub) hazard ratio represents the increase in risk for a one category increment

bWald test

cGray test