Figure 2. GW406108X and GSK2358994A primarily exhibit ATP competitive inhibition against their respective targets.

Michaelis–Menten and Lineweaver–Burke plots showing inhibition of (A) ULK1 by GW406108X and (B) VPS34 by GSK2358994A at varying concentrations of ATP. The data show the average of three independent experiments; error bars indicate the standard deviation.