Table 2.
Effects of YSBGY on osteoblast and osteoclast differentiation-related factors in the peripheral blood of OP mice.
| Groups | CTRL | Dex (30 mg/kg) | YSBGY (10 mL/kg) | |||
|---|---|---|---|---|---|---|
| — | E2 (15 μg/kg) | YSBGY (mL/kg) | ||||
| 5 | 10 | |||||
| Collagen I (ng/mL) | 14.0 ± 0.7 | 10.9 ± 0.7## | 13.5 ± 0.8∗ | 12.1 ± 0.8 | 13.3 ± 0.8∗ | 12.7 ± 0.7 |
| BGP OCN (ng/mL) | 4.30 ± 0.16 | 3.82 ± 0.06# | 4.46±0.14∗∗ | 4.34±0.09∗∗ | 4.62±0.14∗∗ | 4.69 ± 0.10 |
| OPN (ng/mL) | 109.2 ± 3.4 | 94.7 ± 5.6# | 118.4±5.4∗∗ | 119.8 ± 7.3∗ | 121.0±4.0∗∗ | 122.5 ± 5.0 |
| BMP-2 (ng/mL) | 9.60 ± 0.19 | 8.76 ± 0.21# | 9.84 ± 0.33∗ | 9.89 ± 0.31∗ | 10.41±0.34∗∗ | 11.38 ± 1.50 |
| BMPR-2 (ng/mL) | 3.83 ± 0.12 | 3.41 ± 0.12# | 4.21 ± 0.29∗ | 4.10±0.17∗∗ | 4.49±0.13∗∗∗ | 4.42 ± 0.59 |
| TRACP-5β (U/L) | 3.85 ± 0.15 | 4.61 ± 0.26# | 3.86 ± 0.10∗ | 3.54±0.16∗∗ | 3.85 ± 0.18∗ | 3.63 ± 0.08 |
| CTX-1 (ng/mL) | 4.73 ± 0.24 | 3.84 ± 0.22# | 4.65 ± 0.29∗ | 6.31±0.15∗∗∗ | 5.50±0.30∗∗∗ | 4.74 ± 0.27 |
The data were analyzed using a one-way ANOVA and expressed as means ± SEM (n = 10). #P < 0.05 and ##P < 0.01vs. control mice; ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001vs. OP mice.