Table 2.
Association between serum GGT levels and incident diabetes mellitus in the NAGALA study, 2004–2015.
| Nonadjusted | Adjust I | Adjust II | Adjust III | |
|---|---|---|---|---|
| GGT (IU/L) | 1.01 (1.01, 1.01) | 1.01 (1.01, 1.01) | 1.01 (1.00, 1.01) | 1.00 (1.00, 1.01) |
| Serum GGT quintiles | ||||
| Q1 (≤10 IU/L) | 1 | 1 | 1 | 1 |
| Q2 (11–12 IU/L) | 2.02 (1.13, 3.61) | 1.92 (1.07, 3.46) | 1.74 (0.97, 3.13) | 1.39 (0.77, 2.50) |
| Q3 (13–16 IU/L) | 2.49 (1.47, 4.20) | 2.22 (1.30, 3.79) | 1.81 (1.06, 3.10) | 1.15 (0.66, 1.98) |
| Q4 (17–24 IU/L) | 5.95 (3.68, 9.60) | 5.00 (3.00, 8.34) | 3.33 (1.99, 5.58) | 1.76 (1.04, 3.00) |
| Q5 (≥25 IU/L) | 9.27 (5.83, 14.72) | 7.51 (4.54, 12.41) | 4.30 (2.56, 7.20) | 1.83 (1.06, 3.15) |
| P for trend | <0.0001 | <0.0001 | <0.0001 | 0.0097 |
Notes: data presented are HRs and 95% CIs. Adjust I model adjusts for age and gender; adjust II model adjusts for adjust I + smoking status, alcohol intake, body mass index, and systolic blood pressure; adjust III model adjusts for adjust II + fatty liver, triglycerides, alanine aminotransferase, aspartate aminotransferase, and fasting plasma glucose. Abbreviations: GGT, gamma-glutamyl transferase.