Table 2. Key characteristics of hits from the candidate-based RNAi screen.
Genotype | Stock number | Micronuclei % (N) | Equal segregation % (N) | Distance of acentric to nucleus (μm) | Time of acentric segregation (s) |
---|---|---|---|---|---|
y1v1 | 1509 | 17 (24) | 89 (27) | 3.6 (SD = 1.5; N = 15) | 200 (SD = 60; N = 7) |
Comt RNAi | 31666 | 46 (46) | 89 (44) | 3.5 (SD = 1.2; N = 32) | 180 (SD = 50; N = 12) |
Rtnl2 RNAi | 58208 | 53 (32) | 89 (35) | 3.2 (SD = 1.2; N = 23) | 300 (SD = 110; N = 7) |
Shrub RNAi | 38305 | 51 (37) | 69 (32) | 3.8 (SD = 0.7; N = 19) | 225 (SD = 88; N = 13) |
Micronucleation and equal segregation rates, the average distance of acentrics from daughter nuclei at the time of acentric segregation, and the time from anaphase onset to acentric segregation are shown for each hit from our screen. See also Fig. 5.