Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 15;219(3):e201905228. doi: 10.1083/jcb.201905228

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Edwards-Jorquera et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 9. — Trpml activity in vivo. Representative images of mitotic clones labeling pupal hemocytes expressing LifeAct-Ruby and calcium sensor trpml-GCaMP5, revealing the activity of the channel in vivo. (A) Migrating hemocyte containing signal at the rear, which perdures over time, suggesting activity of Trpml from the lysosomes. (B) Hemocyte generating a protrusion where transient spikes of activity arise, which probably corresponds to a phagocytic event. Scale bar in A and B: 10 µm. Full videos are included in Video 9. (C) Proportion of migrating cells with signal at the rear and transient spikes of activity upon engulfment. Values are presented as scatter dot plot indicating mean ± SD (n ≥ 4 independent experiments, n ≥ 2 pupae/experiment).