Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 11;219(3):e201902127. doi: 10.1083/jcb.201902127

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Yang et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 4. — The ESCRT deletion abolished one form of microautophagy. (A–C) Representative TEM images showing three types of microautophagy, including PMN, CMO, and small VM invagination in WT cells after rapamycin (Rapa) treatment. Insets are zoomed-in images showing the small tubular invagination of VM. (D and E) Representative TEM images showing that after Rapa treatment, PMN and CMO still happened in vps27Δ cells, while the small VM invagination was nearly abolished. (G) Frequency of observing small VM invagination in WT and vps27Δ cells after Rapa treatment. (H) Number of small vacuole vesicles per cell in WT and vps27Δ cells after Rapa treatment. (I) Size distribution of small vacuole vesicles. (J) Frequency of observing PMN in WT and vps27Δ cells after Rapa treatment. (K) Frequency of observing CMO in WT and vps27Δ cells after Rapa treatment. LD, lipid droplet; Nu, nucleus; Va, vacuole. White arrowheads highlight small vacuole vesicles. Black scale bar, 0.5 µm; white scale bar, 50 nm.