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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Bioorg Med Chem. 2019 Nov 30;28(4):115237. doi: 10.1016/j.bmc.2019.115237

Table 5:

Microsomal stability of synthesized compounds

Compd. Half-life,
t1/2
(min)		 Clearance,
CLINT
(mL/min/kg)
7-ethoxy-4-methylcoumarin 3.84 325
9. 229.59 5
21. 3.21 389
22. 3.10 402
23. 3.55 351
25. 3.26 383
28. 8.18 153
31. 34.71 36
34. 3.59 347
36. 2.90 431
37. 6.25 199
38. 6.28 199