Comparison 16. Ulipristal acetate (all doses) versus levonorgestrel.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Observed number of pregnancies (all women)	2	3448	Risk Ratio (M‐H, Fixed, 95% CI)	0.59 [0.35, 0.99]
2 Observed number of pregnancies (by risk status)	2	3445	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.35, 0.97]
2.1 High‐risk women	2	171	Risk Ratio (M‐H, Fixed, 95% CI)	0.79 [0.25, 2.46]
2.2 Low‐risk women	2	3274	Risk Ratio (M‐H, Fixed, 95% CI)	0.54 [0.30, 0.97]
3 Observed number of pregnancies (time from intercourse)	2	3447	Risk Ratio (M‐H, Fixed, 95% CI)	0.61 [0.37, 1.00]
3.1 Within 24 h	2	1185	Risk Ratio (M‐H, Fixed, 95% CI)	0.40 [0.15, 1.05]
3.2 24‐48 h	2	1213	Risk Ratio (M‐H, Fixed, 95% CI)	1.33 [0.59, 3.00]
3.3 > 48‐72 h	2	846	Risk Ratio (M‐H, Fixed, 95% CI)	0.34 [0.11, 1.06]
3.4 > 72‐96 h	1	136	Risk Ratio (M‐H, Fixed, 95% CI)	0.23 [0.01, 4.73]
3.5 > 96‐120 h	1	67	Risk Ratio (M‐H, Fixed, 95% CI)	0.32 [0.01, 7.68]
4 Observed number of pregnancies within 0‐72 h	2	3245	Risk Ratio (M‐H, Fixed, 95% CI)	0.63 [0.37, 1.07]
5 Specific side effects	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 Nausea	2	3770	Risk Ratio (M‐H, Fixed, 95% CI)	1.14 [0.93, 1.41]
5.2 Vomiting	1	1549	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.14, 7.07]
5.3 Headache	2	3770	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.87, 1.20]
5.4 Dizziness	2	3770	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.78, 1.45]
5.5 Fatigue	2	3770	Risk Ratio (M‐H, Fixed, 95% CI)	1.22 [0.91, 1.62]
5.6 Breast tenderness	1	1549	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.53, 2.14]
5.7 Diarrhoea	1	1549	Risk Ratio (M‐H, Fixed, 95% CI)	1.09 [0.48, 2.45]
5.8 Spotting/bleeding after treatment	1	1549	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.23, 2.24]
5.9 Abdominal pain	1	2221	Risk Ratio (M‐H, Fixed, 95% CI)	0.76 [0.54, 1.06]
5.10 Lower abdominal pain	1	1549	Risk Ratio (M‐H, Fixed, 95% CI)	1.15 [0.69, 1.90]
5.11 Upper abdominal pain	1	2221	Risk Ratio (M‐H, Fixed, 95% CI)	0.81 [0.53, 1.24]
5.12 Back pain	1	2221	Risk Ratio (M‐H, Fixed, 95% CI)	1.31 [0.80, 2.15]
5.13 Dysmenorrhoea	1	2221	Risk Ratio (M‐H, Fixed, 95% CI)	0.90 [0.73, 1.11]
6 Menses	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
6.1 Early	2	3593	Risk Ratio (M‐H, Fixed, 95% CI)	0.43 [0.37, 0.50]
6.2 Delay	2	3593	Risk Ratio (M‐H, Fixed, 95% CI)	1.65 [1.42, 1.92]