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. 2019 Jan 20;2019(1):CD001324. doi: 10.1002/14651858.CD001324.pub6

Comparison 17. Levonorgestrel split dose, 24 hours versus 12 hours.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Observed number of pregnancy (all women) 1 2060 Risk Ratio (M‐H, Fixed, 95% CI) 0.98 [0.53, 1.82]
2 Observed number of pregnancies (by risk status) 1 2012 Risk Ratio (M‐H, Fixed, 95% CI) 0.98 [0.53, 1.81]
2.1 High‐risk women 1 446 Risk Ratio (M‐H, Fixed, 95% CI) 0.39 [0.13, 1.23]
2.2 Low‐risk women 1 1566 Risk Ratio (M‐H, Fixed, 95% CI) 1.56 [0.71, 3.42]
3 Specific side effects 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.1 Nausea 1 2071 Risk Ratio (M‐H, Fixed, 95% CI) 0.96 [0.72, 1.29]
3.2 Vomiting 1 2071 Risk Ratio (M‐H, Fixed, 95% CI) 0.83 [0.37, 1.85]
3.3 Headache 1 2071 Risk Ratio (M‐H, Fixed, 95% CI) 0.89 [0.58, 1.36]
3.4 Dizziness 1 2071 Risk Ratio (M‐H, Fixed, 95% CI) 1.23 [0.86, 1.74]
3.5 Breast tenderness 1 2071 Risk Ratio (M‐H, Fixed, 95% CI) 0.60 [0.40, 0.91]
3.6 Lower abdominal pain 1 2071 Risk Ratio (M‐H, Fixed, 95% CI) 0.76 [0.53, 1.08]
4 Menses 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.1 Delay 1 1978 Risk Ratio (M‐H, Fixed, 95% CI) 0.79 [0.53, 1.17]