| Methods |
Women 'randomly allocated' to 2 groups. Method of randomisation not reported |
| Participants |
100 women attending the gyn clinic in a general hospital, Fujian, China. Women had regular menstrual periods and a single act of unprotected intercourse within 120 h of attending the clinic |
| Interventions |
Mife 25 mg + MTX 5 mg vs Mife 25 mg, single dose, orally |
| Outcomes |
Observed number of pregnancies, side effects and changes in menstrual pattern |
| Notes |
No mention of post‐randomisation exclusion and loss to follow‐up Observed pregnancy/expected pregnancy/total number of women: Mife + MTX 0/5/50; Mife 1/5/50 |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Mentioned randomisation but description not adequate |
| Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment not mentioned |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Not mentioned |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Post‐randomisation exclusion and loss to follow‐up not reported |
| Selective reporting (reporting bias) |
Low risk |
Planned outcome of pregnancy rate was reported |
| Other bias |
Low risk |
None detected |
