Zuo 1999.
Methods | Double‐blind, randomised trial Random number generation done centrally. Double‐blinded by use of identical placebos | |
Participants | 668 women recruited from 14 family planning clinics in Changsha, China. Women aged < 40 years had regular menstrual periods and attended the clinic within 72 h of a single act of unprotected intercourse | |
Interventions | Mife 10 mg, single dose vs Mife 25 mg, orally | |
Outcomes | Observed number of pregnancies, side effects and changes in menstrual pattern | |
Notes |
|
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Random number generation done centrally |
Allocation concealment (selection bias) | Unclear risk | Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes | Low risk | Double‐blind |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Loss to follow‐up reported |
Selective reporting (reporting bias) | Low risk | Reported planned outcomes |
Other bias | Low risk | None detected |
COC: combined oral contraceptive; Cu‐IUD: copper intrauterine device; EC: emergency contraception; ITT: intention to treat; IUD: intrauterine device; LNG: levonorgestrel; MCH: maternal and child health; Mife: mifepristone; MTX: methotrexate; RCT: randomized controlled trial; UPA: ulipristal acetate; WHO: World Health Organization