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. 2020 Mar 4;15:21. doi: 10.1186/s13020-020-0299-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Effects of QSG on cardiac structure and function by MRI in HF rats after AMI. a Representative MR images of rat hearts at the slice of papillary muscle in short-axis view in the four groups. From left to right was the process from the end of diastole to the end of systole. The anterior wall of the left ventricle in the model group was thinner (red arrow) while ventricular cavity was larger in the model group. After drug treatment, ventricular remodeling was attenuated in QSG and fosinopril group. b Bar graphs of LV parameters in the four groups. Rats in the model group underwent significant drops in EF, FS, LVEDAWT and LVESAWT and increases in LVEDD, LVESD, LVEDV, LVESV compared to the sham group. LVEDD, LVESD, LVEDV and LVESV decreased observably, meanwhile LVEDAWT, LVESAWT, FS and EF increased obviously in QSG and fosinopril group compared with the model group. n = 6 per group. Values are mean ± SE. Asterisks indicates significant differences. **P < 0.01