Table 3.
Differential metabolic pathways identified by MPEA between the V.SC and NV.SC groups
| Pathway | Up | Down | p_hyper |
|---|---|---|---|
| Glycerolipid metabolism | Glycerol | Glycerol 3-phosphate | 0.01 |
| Phenylalanine, tyrosine and tryptophan biosynthesis | 4-Hydroxyphenylpyruvic acid | 0.045 | |
| Tyrosine metabolism | Vanillylmandelic acid | 4-Hydroxyphenylpyruvic acid | 0.08 |
| Ubiquinone and other terpenoid-quinone biosynthesis | 4-Hydroxyphenylpyruvic acid | 0.10 | |
| Pentose phosphate pathway | D-Ribose | 0.23 | |
| Galactose metabolism | Glycerol | 0.27 | |
| Cysteine and methionine metabolism | L-Methionine | 0.31 | |
| Glycerophospholipid metabolism | Glycerol 3-phosphate | 0.35 | |
| Arginine and proline metabolism | 4-Hydroxyproline | 0.36 | |
| Purine metabolism | Uric acid | 0.55 |
Abbreviation: MPEA metabolic pathway enrichment analysis, V.SC schizophrenia patients with violence, NV.SC schizophrenia patients without violence