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. 2020 Mar 4;17:18. doi: 10.1186/s12987-020-00180-w

Table 3.

Comparison of the two patient groups

Shunt insufficiency (N = 14) Secondary non-responder (N = 31) Test and p-value
Age
 Mean (median) ± SD (at the time of surgery) 68.5 (68) ± 8 73.3 (72) ± 4.2

t-test

p = 0.01

Pre-VPS CMI
 Mean (median) ± SD 2.2 (3) ± 1.8 27 (2) ± 2.3

Mann–Whitney test

p = ns

 Kiefer score
  Mean (median) ± SD 7 (7) ± 3.6 6.8 (7) ± 2.3

Mann–Whitney test

p = ns

New diseases during the F/U (stroke, Alzheimer disease, Parkinson disease) 1 (7%) 6 (19%)

Fisher’s exact test

p = ns

Over-drainage requiring valve pressure setting ≥ 100 mmH2O 0 (0%) 5 (16%)

Fisher’s exact test

p = ns

CMI Comorbidity Index, VPS ventriculoperitoneal shunt, F/U follow-up