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. Author manuscript; available in PMC: 2020 Nov 19.
Published in final edited form as: Acc Chem Res. 2019 Oct 8;52(11):3039–3050. doi: 10.1021/acs.accounts.9b00391

Figure 3.

Figure 3.

Methods to produce D-luc. (A) Traditional syntheses to form the key benzothiazole core. (B) A streamlined method to produce D-luc using Appel’s salt (blue). Both routes comprise a condensation reaction with D-cysteine as the final step.